I have had this acute horrific status migraine since Friday, it was a hormonal trigger one, and those are the ones that go on strong no matter what you do. Since I had already used a Triptan on monday, I used my 12 hour release painkiller for Tuesday. Got me though half the day, but it was brutal after. So today, when I got up, I used the 12 hour release one again. It worked a little for a few hours and then not at all. Or I should say it was decreasing the amount of pain I felt but the status migraine was at the intense as hell stage so even that painkiller could not bring the pain down enough the function at work. So I took one of my four hour painkillers, tramacet. And I think that was just a little too strong, since I was almost completely pain free. My head only hurt if I tilted it a certain way or moved it too quickly, but otherwise I was feeling no pain. usually I would say if a painkiller completely knocks out the pain then I have used too much, since the idea is to bring the pain down to a manageable level. But it was awesome. No pain, a bit stoned, and got loads of work done. What amazed me is that they pain did not slowly creep back in. I had actually killed the status migraine with a painkiller. Wow. And it was a good things too, if that status had persisted any longer I would have felt desperate enough to go to the ER and then I would have felt frustrated and depressed when they did not help me.