Probiotics Reduce Stress-Induced Intestinal Flare-Ups This is pretty interesting. I'm actually trying a probiotic supplement as a way to help manage my IBS-D because it is problematic and worse when I have a migraine... have to wonder how much nutrients I'm getting and the whole thing affects my appetite quite a bit. Doctors really do not give you many options for IBS-D and you can get pretty sick fast when this causes problems during a status migraine stretch.
"For those with irritable bowel syndrome who wonder if stress aggravates their intestinal disorder, a new University of Michigan Health System study shows it’s not all in their head.
Researchers revealed that while stress does not cause IBS, it does alter brain-gut interactions and induces the intestinal inflammation that often leads to severe or chronic belly pain, loss of appetite and diarrhea.
Stress has a way of suppressing an important component called an inflammasome which is needed to maintain normal gut microbiota, but probiotics reversed the effect in animal models, according to findings published online ahead of print in Gastroenterology.
“The effect of stress could be protected with probiotics which reversed the inhibition of the inflammasome,” says senior study author and gastroenterologist John Y. Kao, M.D., associate professor of internal medicine at the University of Michigan. “This study reveals an important mechanism for explaining why treating IBS patients with probiotics makes sense.”
Probiotics are live bacteria that help grow the gut-dwelling “good” bacteria that keep pathogens in check, aid digestion and nutrient absorption and contribute to immune function."